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Nevertheless, Zechmann (2020) and Otulak-Kozie et al
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With persistent hypoxia, HIF-1 remains activated and drives abnormal expression of downstream genes, including heme oxygenase-1 ( H O -1 ) (Zhai et al., 2023)
The preservation of neuronal integrity, as indicated by the higher number of neuron numbers in the PPAQ group, further supports the neuroprotective role of quercetin
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