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While detailed human studies are limited, MS involves gut dysbiosis that influences immune regulation, with preclinical data suggesting certain bacterial taxa may modulate neuroinflammatory responses

Zamil et al compared vitamin B12 levels in patients with postadolescent acne and healthy individuals and found an increase in B12 deficiency in the healthy cohort

A good candidate is someone with a clearly defined soft-tissue injury and a willingness to follow a complete recovery plan

They are also involved in the unfolded protein response and immunoproteasome-mediated clearance of misfolded proteins 50

Martin et al., 2007