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Renal Insufficiency: As less than 1% of esomeprazole is eliminated unaltered in the urine, it is not anticipated that the pharmacokinetics of esomeprazole in patients with a renal impairment will differ from those in healthy volunteers

Since diagnosis, the median (range) duration of the disease, motor fluctuations and dyskinesia was 7.9 years (3.712.2 years), 4.3 years (1.28.3 years) and 2.4 years (0.25.3 years), respectively, with very high dopa sensitivity (median: 78.9%

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According to the product information, this blend is designed to support gastrointestinal barrier integrity, healthy mucosal balance, beneficial microbial populations, and balanced immune communication