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The trafficking of BDNF through the RSP is proposed to be essential for its function, as the dysregulation of BDNF trafficking has been implicated in numerous neuronal disorders, as disruptions in sorting receptors, motor protein complexes, or scaffold proteins can impair BDNF targeting to the RSP and reduce activity-dependent secretion [3, 4, 11,12,13,14,15,16,17,18,19,20,21,22]

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Other silybin derivatives are in development, such as the silybinphosphatidylcholine complex, which has shown some efficacy with treatment of non-fatty liver disease (Ferenci, 2016)

Topological Dynamics of GABA A Receptor Subunits The localization of GABA A receptors is a dynamic process, which involves the trafficking of the ion-channel receptors along the surface of the neurons (Choii and Ko, 2018)

Medium-term effect of sublingual l-glutathione supplementation on flow-mediated dilation in subjects with cardiovascular risk factors