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During the evolution of Cyanobacteria and Proteobacteria, GSH-dependent ROS detoxification systems incorporated enzymes that play crucial roles in these mechanisms and use GSH as a cofactor, such as GSH peroxidases, GSH reductases, glutaredoxins, and GSH-S-transferases [41]

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H 2 S as an antiviral defense against COVID-19 Indeed, H 2 S has also demonstrated direct antiviral activity against SARS-CoV-2 through interference with viral entry using the ACE2 and TMPRSS2 machinery

Moreover, in fish, taurine counteracts ROS by increasing antioxidant enzymes such as superoxide dismutase, catalase, and GPx

See 21 CFR 50.3 An Institutional review board (IRB) means any board, committee, or other group formally designated by an institution to review biomedical research involving humans as subjects, to approve the initiation of and conduct periodic review of such research