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It is found naturally in human plasma, saliva, and urine

J Biol Chem 279:891929 Kong AN, Yu R, Hebbar V, Chen C, Owuor E, Hu R, Ee R, Mandlekar S (2001) Signal transduction events elicited by cancer prevention compounds

[5] [6] Individuals taking certain medications may also need higher doses, including those on metformin (commonly prescribed for type 2 diabetes), proton pump inhibitors, or H2-receptor antagonists for extended periods

Haushalter RW

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