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All patients in this group were and remained on diabetes medication

Aside from direct membrane attack, other mechanisms for amyloid antimicrobial activities include the induction of protein aggregation within the bacteria itself leading to death, conformational changes to microbial proteins by amyloid binding, thereby inhibiting their function or agglutination of microbes into large aggregates (Chen et al., 2022)

For instance, Belur Nagaraj and colleagues found that miR-181a is an activator of Wnt/-catenin signaling, driving stemness and chemotherapy resistance in high-grade serous ovarian cancer (HGSOC), thus being a potential target for treating recurrent OC (194)

PMID 21977491