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Description
In a study conducted by Abdelkhalek et al., a new series of thieno[2,3-d]pyrimidine derivatives were designed and synthesized to develop multitarget-directed ligands as dual 15-LOX/COX-2 inhibitors (118)

TB-500: actin/cell migration) with apparent synergistic effects

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There is an urgent need for more effective treatment of depression, not only the disorder is becoming more common, but also it is associated with major health and economic burdens