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The different functional regions of the liver were illustrated by the expression status of glutamine-metabolizing enzymes, such that high levels of GLS were found in the portal region [67,68], while only 7% of hepatocytes expressed GS, and these were found specifically around the central hepatic veins [69]

Candidate reactions for pathway construction were drawn from the combined microbiota and host model, which represents the universe of reactions that could be expressed in the murine gut, if the models are assumed to be complete

Muta, T., Kang, D., Kitajima, S., Fujiwara, T

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