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The RNAi tomato plants produced sterile and aborted pollen having shrunken and distorted structures [172]
Gene therapy pipelines for osteoarthritis: current innovations, operational challenges, and future directions
Their study revealed that induction of biogenesis of siRNA relies on host disease resistance gene of RPS2 and NDR1 necessary for RPS2 specific resistance
doi: 10.1126/scisignal.abm6265 120 YaoFDengYZhaoYMeiYZhangYLiuXet al

However, in PD, dysfunction of astrocytes and iron transporters may lead to selective iron deposition in the substantia nigra pars compacta (SNPC)
