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Excess production of ROS induces oxidative modification of macromolecules in epidermal keratinocytes, inhibits various protein functions, and ultimately affects cell viability [9]

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Cultured hepatocytes exhibit basal GCLC phosphorylation, which increased when treated with DBcAMP or phenylephrine, suggesting GCLC may be under a basal inhibitory tone [128]

miR-100 and miR-125b synergistically inhibit five Wnt antagonists (DKK1, DKK3, ZNRF3, RNF43, and APC2)

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