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10.4103/1008-682X.150847 18 DarmishonnejadZ.Hassan-ZadehV.TavalaeeM.KobarfardF.GharagozlooP.DrevetJ

Grogginess: Morning grogginess suggests either excessive dosing or poor timing

F.de SouzaJ

For example, a critical nucleotide position in RNaseH-recruiting ASOs has been identified recently as a hot spot for adverse ASOprotein interaction, leading to a clear improvement of therapeutic index 14

Reference Hooper, D