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This approach offers the major advantage of bypassing gastrointestinal enzymes and hepatic first-pass metabolism, thereby achieving higher systemic bioavailability of therapeutic peptides

164 Furthermore, a meta-analysis of 31 studies found Alzheimer disease patients had lower DHEA-S levels than individuals without Alzheimer disease

Given the diverse etiologies of liver diseases such as hepatitis, liver fibrosis, personalized medicine enables clinicians to identify the precise causes and pathological types through genomic analysis and advanced imaging techniques, thereby developing more targeted therapeutic strategies [260]

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It will complicate the peak detection of the D-peak of PPG