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Carnitine and acylcarnitines are exchanged between different tissues as metabolic intermediates or signaling molecules, directly or indirectly affecting a variety of metabolic and biological pathways in almost all organs, and have broad impacts on interorgan communication and metabolic cooperation

However, these investigators administered NAC for 24 weekstwice the duration of our studyand found a significant NAC-placebo difference only after week 20, suggesting that mitochondrial supplements might require more time to yield clinical benefit

Baracat, M

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