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By contrast, incubation of Neuro-2a cells with SAMe enhanced PP2A methylation, led to the beneficial accumulation of dephosphorylated tau, and increased secretion of neuroprotective -secretase-cleaved APP fragments [173]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 303.Qaddoumi I., Kocak M., Pai Panandiker A.S., Armstrong G.T., Wetmore C., Crawford J.R., Lin T., Boyett J.M., Kun L.E., Boop F.A., et al

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2017;235:R4361