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Dautres sy sont opposs en faisant remarquer que, normalement, lorganisme synthtise lui-mme la carnitine dont il a besoin, ce qui ne peut tre le cas dune vitamine

However, other studies find no difference in SOD expression between AD and control subjects (378)

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Especially in UPR, although TMAO can selectively activate PERK-mediated UPR by binding to PERK, this does not explain TMAO-mediated aggregation of unfold or misfolded proteins in AD