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Description
Centered on oxidative stress, they form a complex network through multiple signaling pathways, eventually leading to cardiomyocyte apoptosis, myocardial hypertrophy and cardiac fibrosis
From this, the triazole-linked PROTAC was synthesized via azide-alkyne cycloaddition reaction, in the presence of copper (I) iodide (CuI)
This is commonly known as part of methylation
Pacifici GM, Boobis AR, Brodie MJ, McManus ME, Davies DS
[DOI] [PubMed] [Google Scholar] 126.Zhang X., Ren X., Zhang Q., Li Z., Ma S., Bao J., Li Z., Bai X., Zheng L., Zhang Z., et al
