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Compared to 1-MQ, the 5-amino-1-methylquinolinium analog ( 1 ) (IC 50 = 1.2 0.1 M) exhibited a tenfold increased inhibition and was able to reverse the high-fat diet-induced obesity in a mouse model
By merging these analogs, researchers aim to explore how their complementary mechanisms may provide a broader perspective on growth hormone modulation
[DOI] [PubMed] [Google Scholar] 38.Snow V, Barry P, Fitterman N, Qaseem A, Weiss K
