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The GSH/GSSG ratio was lower in diamide-treated hearts, and 4-ClDzp blunted the increase in GSSG seen with diamide alone

Additionally, creatine has shown promising neuroprotective effects in combination with CoQ10 in PD patients (Yang et al., 2009)

Such observations suggest an impairment of the glyoxalase system in AD which may be involved in the vicious circle of amyloid- deposition, AGE formation and oxidative stress associated with this disease

Interestingly, the patients with this NRF2/KEAP1 unbalanced expression show a worse prognosis when considering their overall survival

Five bHLH transcription factors were altered, with three being induced in the Sw-7 line at 21 or 35 dpi, and two being induced in the S-line