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[20] For nutritional deficiency without intrinsic-factor loss, shorter courses-such as 30-100 mcg intramuscularly daily for five to ten days followed by 100-200 mcg monthly-are often sufficient

All mice experiments were conducted under protocols that had been previously reviewed and approved by the University of Calgary's Veterinary Sciences Animal Care Committee (VSACC) with the reference number AC17-0220.Various groups of mice (n=14) were intraperitoneally inoculated

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But in this space, the more common pattern is stacking to compensate for weak evidence, not stacking because combination efficacy is proven