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Supplementation of 400 g/mL Trp in the media reversed the fungal growth with increased fungal dry weight (33.331.53 mg), and sclerotia weight (67.673.06 mg), highlighting Trp starvation as a key factor for reduced growth of the fungus
For in vitro experiments, embryonic rat cardiomyocytes (H9c2 cells) exposed to hypoxia-reoxygenation (HR) showed a time-dependent increase in gp91phox (a marker for ROS production by NADPH oxidases), caspase-3 (a key mediator of apoptosis) expression, and a decrease in the glutathione redox ratio
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