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However, a detailed analysis will focus on the impact of individual viral proteins on metabolism, assuming that LongCovid-19 syndrome is generated by an active chronic viral infection and interference of viral proteins with host metabolism, as is the case with other viruses that enter a state of chronic active infection, such as EBV (2126), CMV (27), HCV (28, 29), HSV (30, 31)

In addition, chronic METH users may be at higher risk for developing Parkinson's disease (PD) than nonusers due to the toxic effects of the drug in the nigrostriatal DA pathway

Peripheral supplementation of MANF has shown potential to reduce infarct volume and neuroinflammation in ischemic stroke models, highlighting its therapeutic promise for other neurological diseases [149]