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This may directly inhibit GPX4 activity, thereby impairing cellular capacity to eliminate lipid peroxides and ultimately inducing ferroptosis ( Figure 2 )

Gut microbiota metabolism and interaction with food components

The risk of developing PD increases with age significantly, impacting roughly 1% of individuals over 60 and as many as 4% of those aged 80 or older 34

2023;6:e2315894

Second, we included RCTs that examined complementary endpoints, providing a comprehensive review of this topic
