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The interest and use of nutraceuticals that can play a supportive role in health and skin aging has increased dramatically in the last 10 years, with products containing vitamin C and E, collagen, omega-3 fatty acids, and antioxidants such as curcumin, glutathione, and resveratrol, which have multiple anti-inflammatory, protective effects against oxidative stress and age-related decline in cellular function [79,80,81]

The major behavioral cause of OSF is chewing areca nut, and the symptoms include severe burning sensation, ulceration, restricted mouth opening, and more
However, it is crucial to approach this treatment under the guidance of a qualified healthcare professional to ensure safety and effectiveness

Kunysz M, Mora-Janiszewska O, Darmochwa-Kolarz D (2021) Epigenetic modifications associated with exposure to endocrine disrupting chemicals in patients with gestational diabetes mellitus

However, C9orf72 contains a hexanucleotide repeat expansion, hence it is distinct from the other ALS/FTD mutations
