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Dual and triple incretin-based co-agonists: novel therapeutics for obesity and diabetes

The 3.48% reduction in apoptotic cells did not reach statistical significance, though the molecular markers (caspase-3, PARP, Bcl-2/Bax) were all significant

These data highlight the exciting potential of cagrilintide to offer an alternative approach for people to lose weight, achieve health-related outcomes and manage their obesity, including a favorable tolerability profile, Timothy Garvey, the studys lead investigator and director of the Diabetes Research Center at the University of Alabama at Birmingham, said in a statement

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That is 6,000 mcg per day of a peptide that saturates receptors at 100 mcg