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At specific time points post wounding, animals were humanely euthanised via CO 2 inhalation and the wounds were harvested for biochemical or histological analysis

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A DNA molecule having a sequence consisting of nucleotides which encode a hepatitis E virus open-reading frame 2 protein, said protein having its amino-terminus at amino acid 112 of open-reading frame 2 and its carboxy-terminus at an amino acid in the range of amino acids 578 to 607 of open reading frame 2