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3), and substantially increased mortality (Fig
[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Qiao Z., Jia X., Wang Y., Wang Y., Zhou Y., Li F., Qu Y., Cheng H
Pathway analysis of the identified differential metabolites was performed using the KEGG database
These osteoclast defects appear to be cell-autonomous, as they could be recapitulated by culturing osteoclast precursors from the global IGF-I KO mice, which showed reduced ability to differentiate into mature osteoclasts (65)
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