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Sunny, Parks, Browning, & Burgess, 2011), raising the question of whether NAFLD progression is accelerated by ER stress arising from this increased flux, and whether diminished hepatic TCA flux in mice lacking MPC activity protects the liver at least in part by alleviating or preventing ER stress

218 Endoplasmic reticulum stress and autophagy One of the primary membrane sources for autophagosomes is the ER, and both the initiation and maturation of autophagosomes are closely associated with ER function

10.1038/ejcn.2012.85 27 DickersonF.OrigoniA.KatsafanasE.SquireA.NewmanT.FaheyJ.et al (2021)

it is unclear whether these cells derive from distinct cancer stem cell-like subpopulations or arise from transient adaptations of a broader tumor cell population (Russo et al., 2024)
