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Panel C: On the left, the chemical structures of dietary omega-6 fatty acids are shown: linoleic acid (18:2n-6) and arachidonic acid (20:4n-6)

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In this process, Comparative Gene Identification-58 (CGI-58), also known as ABHD5 (/-hydrolase domain-containing 5), activates ATGL to initiate TAG hydrolysis, generating DAG, which is further hydrolyzed by hormone-sensitive lipase, while monoacylglycerol lipase completes the final step by converting monoacylglycerol into glycerol and free fatty acids