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As such, regardless of the lifestyle and/or biological causes for Glutathione decline in each person, a decrease in levels can cause an increased susceptibility to many age-related conditions and diseases

Moreover, the continuous release of histamine by mast cells triggers further oxidative stress and activates the NF-B inflammatory pathway, creating a self-perpetuating loop of immune dysfunction

PMID: 30291994

As we age, our natural collagen production begins to slow down