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Liu G, Chen M, Mi N, Yang W, Li X, Wang P, et al

Human studies have mainly focused on safety, how the body handles the peptide, and metabolic markers such as IGF-1 and glucose levels, but have not shown strong evidence of weight loss

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ADCC is another pathway to kill the target cells, especially when patients receive specific mAbs treatment

Conclusion Cagrilintide is a long acting amylin analogue researched through amylin receptor complex pharmacology and measured appetite and weight endpoints