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References Abu-Remaileh M, Wyant GA, Kim C, Laqtom NN, Abbasi M, Chan SH, Freinkman E, Sabatini DM (2017) Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

Recent evidence has suggested that GPx1 and c-Src tyrosine kinases participate in the phosphorylation of IB which, in response to hypoxia, leads to the activation of NF-B elevated in hydrogen peroxide-treated embryonic fibroblasts [50]

Current investigations reveal the crucial role of targeting metabolic reprogramming pathways for the amelioration of kidney disease [36], with emphasis on therapies targeting these pathways

They regulate many biological functions, including hormone production, tissue repair, immune responses, and cell communication

Electroacupuncture (EA) at Zusanli (ST36) can upregulation TJ proteins (ZO-1, Occludin, and Claudin-1) and mucin protein (E-Cadherin, MUC2) to reduce the apoptosis and proliferation of IECs and intestinal permeability, further repair the mucus and epithelial barriers (Liu et al., 2023