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Agard, N

however, these compounds are also valuable to humans due to their diverse pharmacological activities 1

MAPK, Mitogen-activated protein kinase

A role for glutathione as a glutamate reservoir may be a bridge between distinct lines of research that implicate glutamatergic dysfunction and aberrant glutathione levels in neuropsychiatric conditions such as schizophrenia

Coniferyl ferulate blocks the NMDAR/NR2B-CaMKII-MAPKs signaling pathway, inhibits ROS production and mitochondrial apoptosis, while reshapes the intestinal microbiota and microbial metabolism, ameliorates colonic inflammation and alleviates depressive symptoms in mice