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100 L of the serum was mixed with 100 L of precipitant P from Recipe Chemicals and Instruments GmbH (Munich, Germany) and centrifuged for 5 min at 10000 x g

Data availability The source data for the findings of this study are available from the corresponding author upon reasonable request

Similarly, the structure of the dipeptide Val-Tyr complex obtained by co-crystallisation of DAP BII (WT) with angiotensin IV (Val-Tyr-Ile-His-Pro-Phe) (dipeptide complex III, Table S1) is consistent with the above catalytic mechanism

Moreover, supplementing the culture medium with physiological concentrations of copper (20 M) further reduces the LD50 of Cu-GTSM from 1.5 M to 150 nM [286]

Andersen F