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Human synovial fibroblasts coexpress IL-1 receptor type I and type II mRNA

By converting superoxide into hydrogen peroxide that is further cleared by catalase and glutathione peroxidase, SOD preserves glutathione levels, reduces inflammatory stress, and activates Nrf2 signaling, which upregulates the bodys primary detox enzymes

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This review provides an overview of berberine in neurodegenerative diseases and its related mechanisms, and also provides new ideas for future research on berberine

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