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Other potential concerns associated with tirzepatide: Birth control interactions: Tirzepatide may reduce the effectiveness of oral hormonal birth control, such as desogestrel, ethinyl estradiol, and levonorgestrel, so it is recommended to switch to non-oral contraceptives before starting tirzepatide

Common Symptoms Include: Fatigue and Weakness: Low B12 affects red blood cell production, leading to reduced oxygen delivery and persistent tiredness

The most common starting protocol is 250 mcg twice daily

Reported side effects are generally mild, but long-term safety data in humans is still limited