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No se ha descrito efectos nutricionales con su uso, pero lleva poco tiempo en el mercado y en la historia de los frmacos se ha visto que los efectos adversos se pueden observar algunos aos despus de que su uso se ha masificado
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Feeding APOC3 knockout mice with a high fat diet for two weeks failed to stimulate VLDL-TG production, while reconstitution of APOC3 expression using adenovirus encoding human apoC3 resulted in robust production of VLDL-TG [69]

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