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In PD, complex I deficiency is the main cause of ROS generation, while ROS are mainly generated in complex I and complex III (Kussmaul and Hirst 2006)

10.3390/antiox11020209 106 OyeleyeS

Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism

Ethics declarations Competing Interest The authors declare no competing interests

Finally, we highlight the latest research developments concerning iron-regulated therapeutic agents and rational treatment strategies aimed at targeting ferroptosis
