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The remaining nitrogen enters the portal vein either as ammonia or as alanine, both of which are used by the liver for the synthesis of urea ( Chapter 19 )
GH-axis manipulation can complicate insulin sensitivity and fluid balance in some individuals

Thats normal: animal studies are used to get a sense of what a compound does and to get a sense of its safety

Konno K, Arai H, Motomiya M, et al

Saleh, M
