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doi: 10.1016/j.dmpk.2019.08.002

2019;8:e1574198

doi: 10.1136/gutjnl-2021-324032 73 MerwinN

Niacinamide: Helps improve the appearance of even skin tone, freshness, and clarity

Packaging stability determines whether stated peptide concentrations remain active throughout product shelf life rather than degrading into ineffective fragments - opaque tubes or airless pumps protect light-sensitive peptides, small sizes (15ml typical for eye products) ensure use before significant degradation occurs, and refrigeration recommendations suggest manufacturers prioritize active potency over extended ambient shelf life