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19,20 The use of EPO and ESAs has been reported in different sports, such as the well-known cases in cycling, 21 athletics, 22 and more recently mixed martial arts (MMA)
The regions industrialization has contributed to chemical runoff and wastewater discharges, which could potentially threaten the lakes delicate ecosystem

doi: 10.1200/JCO.1991.9.3.371 66 MikiY.TaketomiY.KidoguchiY.YamamotoK.MuramatsuK.NishitoY.et al

Key transcription factors that regulate the expression of these genes include NF-E2 related factor 2 (Nrf2) via the antioxidant response element (ARE), AP-1, and nuclear factor kappa B (NFB)

The most well-documented effect involves the GABAergic system