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The European Journal of Contraception & Reproductive Health Care

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EP2139488A1 USE OF RIBOFLAVIN IN THE TREATMENT OF HYPERTENSION

Of these three, two, L-glutamine and crizanlizumab, were approved as a consequence of their efficacy in reducing the frequency of vaso-occlusive events, while the third, voxelotor, was approved due to its ability to improve anemia by reducing hemolysis, without regard to any effect on vaso-occlusive events

This had long been described in terms of spontaneous Ca 2+ signals, which are present in astrocytes across several brain regions and developmental stages (Aguado et al., 2002)