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Normal TIGAR upregulated the production of NADPH, thereby reducing the level of ROS in cells and the sensitivity of cells to apoptosis-related oxidative stress [96]

Nat Chem Biol 13:8190
10.3390/antib6040016 93 DuffyM

This patient's thrombotic presentation with calf swelling and hypoxemia directly contradicts a bleeding disorder

The genetic test does not predict which peptide will work best or guarantee response, but variants in GH pathway genes may support a more nuanced conversation between patient and provider about individual metabolic potential and baseline risk factors for peptide-related side effects
