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A high F/B ratio is associated with an increased risk of metabolic problems in the host, as it is usually associated with an inflammatory state

Moreover, daratumumabs activity was validated in newly diagnosed MM patients [73] and those with intermediate-risk/ high-risk smoldering MM [74]

CD69 is an early and transient activation marker following B cell activation, and is important for retention of lymphocytes in the lymph node (Gonzlez-Amaro et al, 2013)

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