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Future direction should also prioritize patient stratification using biomarkers such as the levels of p53, MT2A, or LDH, the hypoxic or redox status, and mutations in ARID1A or SF3B1 , in which glycolytic remodeling or copper homeostasis serves as determinants of therapeutic efficacy
[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Tang F, Hughes JA

These are general laboratory handling notes drawn from published peptide-chemistry practice

Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide