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Four of the 36 patients tested experienced mild adverse events such as blepharitis, keratitis, hyperemia, and ocular irritation, all of which resolved within 72 h
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Mice were fed a tamoxifen citrate containing diet for three weeks following the protocol of Kiermayer et al .40 to delete Gpx4
Under normoxic conditions, Nrf2 binds to Keap1 and continues to be inactivated by ubiquitination and degradation in the proteasome (Lu et al., 2017)
