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2018, doi:10.1155/2018/1968450 Tabrizi R, Ostadmohammadi V, Lankarani KB, et al

ROS are highly reactive molecules that occur naturally as byproducts of cellular metabolism and aerobic respiration

Acknowledgements We would like to thank the drawing tools provided by Figdraw

Through these main mediators, IL-6 plays an important role as a pleiotropic cytokine, and there are many studies on IL-6 that have shown significant evidence of this cytokine in COPD pathology, with all COPD patient groups showing correlations between IL-6 levels, disease severity, exacerbations, skeletal muscle depletion, cachexia, cardiovascular disease, and all-cause mortality [31, 32]

doi: 10.1111/bph.15838 [DOI] [PubMed] [Google Scholar] 184.Oh YJ, Lee YJ, Lee E, et al