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There are several theories behind this that involve a combination of improved muscle oxygenation, endogenous release of opioids via muscle contractions, reduced hyperactivity of the sympathetic system, and improvement in psychosociological factors [12]

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Recommended use: Take one portion daily (~2 teaspoons = 10 ml), preferably 30 minutes before exercise

their efficacy has not been fully assessed [151] and the amount prescribed in cross sectional and cohort studies varies between 15-50% of total protein intake [11],[23],[25],[151],[159],[160], partly influenced by metabolic stability, natural protein intake tolerated, patient age, disorder severity and local practice