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In an inflammatory state, endothelial cells undergo activation, promoting platelet activation and adhesion [99] and localized inflammation by recruiting pro-inflammatory agents and increased leukocyte transmigration [97,98] (Fig

ACKNOWLEDGMENTS AND DISCLOSURES Julie Carillon was supported by a CIFRE grant (Convention Industrielle de Formation par la Recherche, n 0417/2010) from the French Association Nationale de la Recherche et de la Technologie and Bionov (Avignon, France), which produces and commercializes an antioxidant product

These responses can be additionally differentiated in a cell-specific manner due to the presence of nine known subtypes of those receptors, 1 (1A, 1B, 1D), 2 (2A, 2B, 2C), and ( 13) [78]

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