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Collectively, these studies suggest that complement regulation does play a modest role in determination of outcome in experimental Lyme borreliosis, but that additional Borrelia virulence determinants contribute to the host-pathogen standoff of persistent infection

doi: 10.1073/pnas.0706625104 235 ZhangJZhangFZhaoCXuQLiangCYangYet al

Additionally, studies employing cortical pattern matching have shown diminished cortical gray matter thickness in the left anterior cingulate cortex among individuals with T2DM, with those co-diagnosed with major depression exhibiting significant cortical gray matter reductions in bilateral prefrontal areas when compared to healthy controls [102]

Therefore, the self-elimination effect of mitophagy influences tissue regeneration

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